Wetenschap.onderzoek

Met wetenschap en Cannabis tegen Alzheimer en dementie!

'De meeste mensen krijgen het er een beetje mistig in hun hoofd van, maar de wetenschappers onderzochten of een werkzame stof in cannabis daadwerkelijk dementie kon afwenden.' schreef de Sydney Morning Herald afgelopen woensdag.

De Australische neurowetenschappers onderzochten het effect van werkzame stoffen van cannabis en of deze (Alzheimer) dementie kunnen voorkomen en/of terugdringen.

Cannabidiol

Het gaat om één van de belangrijkste actieve ingrediënten in cannabis, Cannabidiol genoemd.

Volgens de neurologen die bij het onderzoek betrokken waren, heeft de werkzame stof Cannabidiol de eigenschappen die heilzaam zijn voor de hersenen en hebben ook de mogelijkheid om geheugenverlies tegen te gaan.

De werkzame stof Cannabidiol

Bij een wetenschappelijk onderzoek met muizen waarbij een vroege stadia van Alzheimer dementie gesimuleerd werd- en waarbij de muizen Cannabidiol ingespoten kregen, controleerden de onderzoekers wat er zou gebeuren wanneer de hersencellen van muizen behandeld werden met het geneesmiddel.

Het onderzoek heeft aangetoond dat Cannabidiol wel degelijk werkt. De proefdieren vertoonden een flinke vooruitgang bij proeven waarbij vooral naar het geheugen en het vermogen tot herkenning gekeken werd.

Tim Karl, een senior onderzoeker, zei dat Cannabidiol niet dezelfde psychoactieve effecten als THC, de belangrijkste component van marihuana heeft, maar het is gebleken dat Cannabidiol wel de anti-inflammatoire, anti-oxidant en andere nuttige effecten heeft die goed zijn voor de hersenen.

"Het gedrag en presteren van de proefdieren kwam terug naar het niveau van gezonde dieren. Je zou kunnen zeggen dat ze genezen waren, maar er is meer onderzoek vereist om dit met zekerheid vast te kunnen stellen", aldus Tim Karl.

"Vroeger, 100 á 200 jaar terug. werd cannabis als medicijn gebruikt, maar op een gegeven werd er ontdekt dat het ook andere effecten heeft en besloot men, zoals het al te vaak in de moderne maatschappij gebeurt, om het een 'slechte drug' sticker te plakken", zei hij.

De resultaten van het onderzoek worden deze week gepresenteerd tijdens de jaarlijkse bijeenkomst van de Australian Neuroscience Society in Melbourne.

Naast Cannabidiol zijn er ook andere werkzame stoffen van cannabis bekend, o.a. tetrahydrocannabinol (THC) dat invloed heeft op het bewustzijn (het 'stoned' effect)

Medicinale gebruik van Cannabis in Nederland

Vanaf 1 september 2003 is in Nederland medicinaal gebruik van Cannabis toegestaan- en is Marihuana op doktersrecept bij een apotheek verkrijgbaar.
Medicinale gebruik van cannabis kan verlichting geven van klachten (vooral pijn) die zich voordoen bij een aantal aandoeningen, o.a:

Multiple sclerose (met ernstige spierspasmen)
Misselijkheid en braken door chemotherapie, radiotherapie en gecombineerde hiv-therapie
Chronische zenuwpijn
Het syndroom van Gilles de la Tourette
Als pijnstiller bij behandelingen van kanker en aids
Slaapproblemen
Hoofdpijn/Migraine
Verlaging van de oogdruk bij glaucoom

Met wietolie tegen kanker

Diverse wetenschappelijke onderzoeken beweren daarnaast, dat sommige stoffen in Cannabis eveneens kunnen optreden als potentiële kankerkillers.

Zo wordt hier (zie artikel hieronder) beweerd dat Cannabis verspreiding van borstkanker stopt, maar al veel langer wordt er beweerd dat Cannabinoïden, de actieve bestanddelen van marihuana, tumoren kunnen voorkomen en kankercellen kunnen vernietigen. Meer daarover leest u o.a. hier (zie engelstalig artikel hieronder).

Daardoor is Wietolie razend populair geworden onder kanker patiënten wereldwijd, ongeacht of het landen betreft waar Wiet door de Staat als legaal of illegaal beschouwd wordt.

Maripharm en gestandaardiseerde geneesmiddelen uit Cannabis

In 1995 is Maripharm opgericht, met het doel gestandaardiseerde geneesmiddelen uit Cannabis te ontwikkelen. Vanwege de vraag van patiënten leverde Maripharm tot 2003 Medicinale Graad Cannabis (MGC) op doktersrecept aan meer dan 1000 apothekers door heel Nederland, maar is in 2003 wegens technische redenen niet gecontracteerd als leverancier van overheidscannabis.

Sindsdien ligt de nadruk op het verder ontwikkelen en onderzoeken van cannabis en cannabinoiden. Maripharm heeft van het ministerie van VWS een opiumontheffing gekregen om cannabis te telen en te bewerken voor wetenschappelijk onderzoek.

Maripharm is het enige ISO-gecertificeerde bedrijf in Nederland dat zich met cannabis en cannabinoden bezig houdt en is gecertificeerd voor zowel de productie als de distributie van cannabis. Volgens een bericht op kanker-actueel.nl, anno 2011 is marihuana nog steeds te verkrijgen via de apotheek. Hiervoor zijn wel doktersvoorschriften en dure vergunningen vereist.

Bron:http://nieuws.openhandel.nl/76380/154/Met_wetenschap_en_Cannabis_tegen_Alzheimer_dementie!/

'Cannabis stopt verspreiding borstkanker'

Een bestanddeel dat te vinden is in de cannabisplant kan de verspreiding van vele vormen van agressieve kanker stoppen. Dat stellen Amerikaanse wetenschappers.

Onderzoekers ontdekten dat het bestanddeel genaamde cannabidiol genen kan 'uitschakelen' die verantwoordelijk zijn de uitzaaiing van agressieve vormen vanborstkanker. De stof heeft bovendien niet de psychoactieve eigenschappen van de cannabisplan, de patiënt wordt er dus niet stoned van.

Hoewel er nog veel onderzoek nodig is voordat het medicijn als pil op de markt kan komen worden er al wel proefmodellen voor mensen ontwikkeld. De onderzoekers hopen de modellen uiteindelijk te testen naast de huidige chemokuren.

Bron: The Daily Mail

Cannabinoids Kill Cancer And Our 'Government' Has Known for 36 Years

Below is a repost of an article published on Americans for Safe Access website: www.safeaccessnow.org in November of 2003. The article describes how cannabinoids, the active components of marijuana, inhibit tumor growth in laboratory animals and also kill cancer cells. Then it finishes off by saying that the US government has known for more than 35 years and that the media which would normally go crazy about a cancer cure story like this, doesn't at all and in fact seem to be burying the story rather than promote it in any way. I for one am amazed at the government's stance on marijuana and their failed war on drugs, which is more like a war on it's own country. I guess too many people get rich off of the war on drugs.

by Steve Kubby, Sierra Times

November 10th, 2003

A new study published in Nature Reviews-Cancer provides an historic and detailed explanation about how THC and natural cannabinoids counteract cancer, but preserve normal cells.

The study by Manuel Guzmán of Madrid Spain found that cannabinoids, the active components of marijuana, inhibit tumor growth in laboratory animals. They do so by modulating key cell-signalling pathways, thereby inducing direct growth arrest and death of tumor cells, as well as by inhibiting the growth of blood vessels that supply the tumor.

The Guzman study is very important according to Dr. Ethan Russo , a neurologist and world authority on medical cannabis: "Cancer occurs because cells become immortalized; they fail to heed normal signals to turn off growth. A normal function of remodelling in the body requires that cells die on cue. This is called apoptosis, or programmed cell death. That process fails to work in tumors. THC promotes its reappearance so that gliomas, leukemias, melanomas and other cell types will in fact heed the signals, stop dividing, and die."

"But, that is not all," explains Dr. Russo: "The other way that tumors grow is by ensuring that they are nourished: they send out signals to promote angiogenesis, the growth of new blood vessels. Cannabinoids turn off these signals as well. It is truly incredible, and elegant."

In other words, this article explains several ways in which cannabinoids might be used to fight cancer, and, as the article says, "Cannabinoids are usually well tolerated, and do not produce the generalized toxic effects of conventional chemotherapies.

Usually, any story that even suggests the possibility of a new treatment for cancer is greeted with headlines about a "cancer cure" however remote in the future and improbable in fact it might be. But if marijuana is involved, don't expect any coverage from mainstream media, especially since mainstream editors have been quietly killing this story for the past thirty years

That's right, news about the abilility of pot to shrink tumors first surfaced, way back in 1974. Researchers at the Medical College of Virginia, who had been funded by the National Institutes of Health to find evidence that marijuana damages the immune system, found instead that THC slowed the growth of three kinds of cancer in mice - lung and breast cancer, and a virus-induced leukemia.

The Washington Post reported on the 1974 study - in the "Local" section - on Aug. 18, 1974. Under the headline, "Cancer Curb Is Studied," it read in part: "The active chemical agent in marijuana curbs the growth of three kinds of cancer in mice and may also suppress the immunity reaction that causes rejection of organ transplants, a Medical College of Virginia team has discovered." The researchers "found that THC slowed the growth of lung cancers, breast cancers, and a virus-induced leukemia in laboratory mice, and prolonged their lives by as much as 36 percent."

"News coverage of the Madrid discovery has been virtually nonexistent in this country. The news broke quietly on Feb. 29, 2000 with a story that ran once on the UPI wire about the Nature Medicine article," complained MarijuanaNews.com editor Richard Cowan , who said he was only able to find the article through a link that appeared briefly on the Drudge Report Web page. "The New York Times, The Washington Post, and Los Angeles Times all ignored the story, even though its newsworthiness is indisputable: a benign substance occurring in nature destroys deadly brain tumors," added Cowan.

On March 29, 2001, the San Antonio Current printed a carefully researched, bombshell of a story by Raymond Cushing titled, "POT SHRINKS TUMORS; GOVERNMENT KNEW IN '74." Media coverage since then has been nonexistant, except for a copy of the story on Alternet.

It is hard to believe that the knowledge that cannabis can be used to fight cancer has been suppressed for almost thirty years , yet it seems likely that it will continue to be suppressed. Why?

According to Cowan, the answer is because it is a threat to cannabis prohibition .

"If this article and its predecessors from 2000 and 1974 were the only evidence of the suppression of medical cannabis, then one might perhaps be able to rationalize it in some herniated way. However, there really is massive proof that the suppression of medical cannabis represents the greatest failure of the institutions of a free society, medicine, journalism, science, and our fundamental values," Cowan notes.

Millions of people have died horrible deaths and in many cases, familes exhausted their savings on dangerous, toxic and expensive drugs. Now we are just beginning to realize that while marijuana has never killed anyone, marijuana prohibition has killed millions.

http://rense.com/general93/canna.htm

Wetenschappelijke onderzoeken cannabis en kanker

There’s still a lot of confusion across the nation about whether or not marijuana is effective for cancer patients. Odds are you’ve heard something about it but weren’t sure whether the information was reliable or definitive. So, in order to help clear things up, here is a list of 34 studies showing that marijuana cures cancer, categorized by the type of cancers being cured in each study. As you sort through the articles, note that the consistent theme between them is that cannabis shrinks tumors and selectively targets cancer cells. As bills and voter initiatives to legalize medical marijuana spread from state to state, remember that we’re not just talking about mitigating the side effects of chemo (though this is another viable use), we’re talking about curing the cancer itself as well as preventing its spread. I’ve taken the liberty of only including articles from credible scientific journals, removing any biased or otherwise improperly cited studies. Enjoy!

Cures Brain Cancer

http://www.nature.com/bjc/journal/v95/n2/abs/6603236a.html

http://www.ncbi.nlm.nih.gov/pubmed/11479216

http://www.jneurosci.org/content/21/17/6475.abstract

http://jpet.aspetjournals.org/content/308/3/838.abstract

http://mct.aacrjournals.org/content/10/1/90.abstract

Cures Mouth and Throat Cancer

http://www.ncbi.nlm.nih.gov/pubmed/20516734

Cures Breast Cancer

http://www.ncbi.nlm.nih.gov/pubmed/20859676

http://www.ncbi.nlm.nih.gov/pubmed/18025276

http://www.ncbi.nlm.nih.gov/pubmed/21915267

http://www.molecular-cancer.com/content/9/1/196

http://www.ncbi.nlm.nih.gov/pubmed/22776349

http://www.pnas.org/content/95/14/8375.full.pdf+html

Cures Lung Cancer

http://www.ncbi.nlm.nih.gov/pubmed/22198381?dopt=Abstract

http://www.ncbi.nlm.nih.gov/pubmed/21097714?dopt=Abstract

http://www.nature.com/onc/journal/v27/n3/abs/1210641a.html

Cures Uterine, Testicular, and Pancreatic Cancers

http://www.cancer.gov/cancertopics/pdq/cam/cannabis/healthprofessional/page4

http://cancerres.aacrjournals.org/content/66/13/6748.abstract

Cures Prostate Cancer

http://www.ncbi.nlm.nih.gov/pubmed/12746841?dopt=Abstract

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3339795/?tool=pubmed

http://www.ncbi.nlm.nih.gov/pubmed/22594963

Cures Colorectal Cancer

http://www.ncbi.nlm.nih.gov/pubmed/22231745

Cures Ovarian Cancer

http://www.aacrmeetingabstracts.org/cgi/content/abstract/2006/1/1084

Curse Blood Cancer

http://www.ncbi.nlm.nih.gov/pubmed/12091357

http://www.ncbi.nlm.nih.gov/pubmed/16908594

http://onlinelibrary.wiley.com/doi/10.1002/ijc.23584/abstract

http://molpharm.aspetjournals.org/content/70/5/1612.abstract

Cures Skin Cancer

http://www.ncbi.nlm.nih.gov/pubmed/12511587

Cures Liver Cancer

http://www.ncbi.nlm.nih.gov/pubmed/21475304

Cures Biliary Tract Cancer

http://www.ncbi.nlm.nih.gov/pubmed/19916793

Cures Bladder Cancer

http://www.medscape.com/viewarticle/803983 (Sign-up required to view study)

Cures Cancer in General

http://www.ncbi.nlm.nih.gov/pubmed/12514108

http://www.ncbi.nlm.nih.gov/pubmed/15313899

About the Author

Michael Taillard, professional economist, published author and board member of NORML Nebraska.

This post is courtesy of The Joint Blog. Please give them a visit sometime.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of WakingTimes or its staff.

New Study Shows Cannabinoids Improve Efficiency Of Mitochondria And Remove Damaged Brain Cells

A recent study conducted by Andras Biokei-Gorzo at the Institute of Molecular Psychiatry at the University of Bonn in Germany is suggesting that marijuana(or the activation of the brain’s cannabinoid system) triggers the release of antioxidants, which act as a cleansing mechanism. This process is known to remove damaged cells and improve the efficiency of mitochondria. Mitochondria is the energy source that powers cells. The study was published in Philosophical Transactions Of The Royal Society, B. You can read the entire study here.

These discoveries shed new insight on how natural marijuana cannabinoids hold the capacity to literally kill the brain inflammation responsible for causing cognitive decline, neural failure, and brain degeneration. By supplying these receptor sites with cannabinoids, patients may be able to overcome brain conditions like Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, and more, not to mention premature brain aging. The human brain contains an extensive network of special receptor sites that modulate nervous system function only when activated by the appropriate cannabinoid compounds, which are found in the marijuana plant.

Cannabinoids refer to any of a group of related compounds that include cannabinol and the active constituents of cannabis. They activate canbinoid receptors in the body. The body itself produces compounds called endocannabinoids and they play a role in many processes within the body that help to create a healthy environment. Cannabinoids also play a role in immune system generation and re-generation. The body regenerates best when it’s saturated with Phyto-Cannabinoids. Cannabinoids can also be found in Cannabis. Cannabinoids may very well be the best cancer fighting substance out there!

Cannabinoid system activity is neuroprotective, and increasing it could be a promising strategy for slowing down the progression of brain aging and for alleviating the systems of neurodegenerative disorders -Andras Biokei

Gery Wenk, a professor of neuroscience, immunology and medical genetics at Ohio State University conducted some of the research that came out of the study from Germany. He stated that this is a positive step, and that it is encouraging to see the potential development of cannabinoid solutions without going overboard. Here is what he said.

I’ve been trying to find a drug that will reduce brain inflammation and restore cognitive function in rats for over 25 years; cannabinoids are the first and only class of drugs that have ever been effective. I think that the perception about this drug is changing and in the future people will be less fearful. – Gerry Wenk, Professor of neuroscience, immunology and medical genetics at Ohio State University

Biokei-Gorzo and his collegues said that the greatest hurdle for moving forward with their research are the social and political challenges. This isn’t something new, our world seems to be dominated by belief systems instead of obvious fact. It’s discouraging to see beliefs and persuasion overrule truth. At the same time it’s very encouraging to see truth slowly creep its way into the norm. That’s always how it has been done throughout human history. It’s quite evident that the powers that be do not want to legalize marijuana, and we know that they do not have our best interest at hand. If it was legalized, I’m sure it would be distributed and tweaked by big pharmaceutical companies.

On the other hand there have been a number of studies that show how marijuana can actually reduce brain power and impair working memory. The amount of studies that show the potential benefits of marijuana is outstanding, and the potential harmful effects are in the few, if any at all. As far as medicinal use goes, I think that is a no brainer. I definitely believe nature intended marijuana to be used for its health and healing properties.

Sources:

http://rstb.royalsocietypublishing.org/content/367/1607/3326.abstract?sid=20cf2c23-e4fd-49e3-9398-ec8be2e00226

http://healthland.time.com/2012/10/29/how-cannabinoids-may-slow-brain-aging/

http://www.drugscience.org/Petition/C3D.html

http://www.naturalnews.com/040456_marijuana_cannabinoids_dementia.html

http://www.rawhemp.tk/

http://www.phoenixtears.ca/

http://cannabisinternational.org/

http://edrv.endojournals.org/content/27/1/73.full http://cannabisclinicians.org/wp-content/uploads/2011/12/OS-2011-Terpenes+Minor-CBs.pdf

Cognitive Dysfunction - Alzheimers Disease - Cannabinoid Research

Wetenschappelijke onderzoeken naar werking cannabinoiden bij Alzheimer, ontstekingen enz. (Engelstalig)

Published on Apr 3, 2013